China Top 8 Hydroxy 5 Nitroquinoline Supplier?
China has become an important sourcing base for specialty quinoline intermediates, supported by broad chemical manufacturing capacity and export infrastructure. This article examines potential Chinese suppliers of 8 Hydroxy 5 Nitroquinoline through practical, verifiable criteria. These include product identity, assay, impurity control, production experience, and documentation quality.
Reliable sourcing requires more than a polished website. The OECD eChemPortal recommends checking authoritative chemical information and hazard data before procurement. ECHA’s Information on Chemicals database also highlights the value of substance identification, classification, and responsible handling records. These references provide useful direction, although they may not contain complete information for this niche compound.
Small details matter. A serious supplier should provide a current Certificate of Analysis, batch number, test method, and storage guidance. HPLC purity data should match the offered specification. Packaging should protect the material from moisture, heat, and contamination during transport. ISO 9001 certification can support quality management, but it does not automatically prove product quality.
Documentation matters most.
The review also considers manufacturing transparency, sample responsiveness, minimum order quantities, lead times, and international shipping experience. Public trade data, including UN Comtrade, can help explain broader chemical export patterns, but it rarely confirms the quality of one specific product. That limitation deserves honesty. A supplier ranking cannot replace independent testing or a technical audit.
Readers should therefore treat this guide as a structured starting point, not a final purchasing decision. Each candidate should be verified against the buyer’s application, quality requirements, and applicable chemical regulations. The safest choice is usually the supplier that communicates clearly, supplies consistent batches, and accepts reasonable verification.
What Is 8-Hydroxy-5-Nitroquinoline?
8-Hydroxy-5-nitroquinoline is a substituted quinoline compound with two functional groups. A hydroxyl group appears at position 8, while a nitro group occupies position 5. PubChem lists its molecular formula as C9H6N2O3 and molecular weight as 190.16 g/mol. These figures help laboratories verify identity before purchasing or testing a sample.
Its fused aromatic structure supports strong ultraviolet absorption and metal-binding behavior. However, performance depends on purity, particle form, solvent history, and storage conditions. A pale yellow powder may look acceptable, yet appearance alone proves very little. OECD chemical-testing guidance emphasizes reliable substance identification, impurity control, and documented analytical methods. For this reason, buyers should request a current certificate of analysis, HPLC purity, water content, residual solvents, and spectroscopic data.
Quality assessment needs practical evidence. Ask for batch-specific results, not a recycled specification sheet. Check whether the reported molecular weight matches 190.16 g/mol. Confirm that the supplier can provide traceable sampling and stable packaging. Small inconsistencies matter. One overlooked impurity can change experimental results, especially in analytical or coordination studies. Public databases provide useful identity data, but they do not replace independent verification, risk assessment, or application-specific validation.
China Top 8 Hydroxy 5 Nitroquinoline Supplier? - What Is 8-Hydroxy-5-Nitroquinoline?
| No. |
Data Dimension |
Information |
Practical Relevance |
| 1 |
Chemical identity |
8-Hydroxy-5-nitroquinoline, also written as 5-nitroquinolin-8-ol |
The name identifies a quinoline ring containing a hydroxyl group at position 8 and a nitro group at position 5. |
| 2 |
CAS Registry Number |
4008-48-4 |
A unique identifier used for confirming the chemical identity during purchasing, documentation, and quality control. |
| 3 |
Molecular formula |
C9H6N2O3 |
The formula indicates the elemental composition used for molecular-weight calculations and analytical verification. |
| 4 |
Molecular weight |
190.16 g/mol |
This value is useful for preparing solutions, calculating stoichiometric quantities, and interpreting mass-spectrometric results. |
| 5 |
Functional groups |
Heteroaromatic nitrogen, phenolic hydroxyl, and aromatic nitro groups |
These groups influence polarity, hydrogen bonding, metal-ion coordination, and chemical reactivity. |
| 6 |
Typical physical form |
Yellow to orange crystalline solid or powder, depending on purity and processing history |
Color and physical form can provide an initial indication of material consistency but should not replace instrumental testing. |
| 7 |
Solubility profile |
Generally limited in water; solubility may improve in suitable polar organic solvents or alkaline media |
Solvent compatibility should be checked before synthesis, formulation, extraction, or analytical sample preparation. |
| 8 |
Recommended supplier-quality checks |
Verify CAS number, molecular formula, assay, water content, residual solvents, heavy metals, impurity profile, SDS, and certificate of analysis |
These checks help compare China-based supply options without relying only on product descriptions or stated purity. |
Note: Physical descriptions and solubility information are general literature-based characteristics. Confirm the current specification, analytical data, handling requirements, and regulatory documents for each individual batch before use.
Key Properties, Uses, and Industrial Applications
Hydroxy 5 Nitroquinoline is a heteroaromatic compound containing hydroxyl, nitro, and quinoline groups. These functional groups influence its color, polarity, and chemical reactivity. It commonly appears as a yellow to orange crystalline powder, although shade may vary between batches. Water solubility is usually limited. Solubility improves in selected polar organic solvents, depending on temperature and formulation conditions.
Industrial users mainly treat this material as a specialty intermediate for chemical research and controlled synthesis. Its quinoline structure supports applications in material development, analytical studies, and the preparation of more complex functional molecules. In some laboratories, researchers examine its coordination behavior with selected metals. That area needs careful method control. Results can change with pH, solvent purity, and storage time.
When assessing a Chinese supplier, buyers should request a current certificate of analysis, HPLC data, moisture results, and impurity limits. Packaging should protect the powder from light, humidity, and unnecessary temperature changes. Production records and batch traceability matter. A small sample test is wise before larger procurement. One overlooked issue is particle-size variation, which may affect weighing and dispersion. Supplier claims alone are not enough. Independent verification remains useful. Safety data, compliant labeling, and documented transport procedures should accompany every commercial shipment.
How to Evaluate Chinese 8-Hydroxy-5-Nitroquinoline Suppliers
Choosing a top Chinese 8-Hydroxy-5-Nitroquinoline supplier requires more than comparing online prices. Cefic’s 2024 Facts and Figures report estimates that China represented about 40% of global chemical sales in 2023. That scale offers strong manufacturing capacity, but it does not guarantee consistent quality.
Request a current Certificate of Analysis for every batch. Check assay, water content, melting range, residual solvents, and test methods. Ask whether results come from an independent laboratory. ISO Survey 2022 recorded more than 400,000 ISO 9001 certificates in China, yet certification alone cannot prove product performance. Review the actual scope, audit date, and quality records.
A reliable supplier should provide a clear Safety Data Sheet, traceable batch numbers, packaging photographs, and storage conditions. Confirm production capacity with realistic lead times, not vague promises. For international purchasing, review customs documents and transport classifications before signing. OECD due-diligence guidance supports documented risk checks across the supply chain. Request a small sample first. Then compare two or three batches.
Communication quality matters. Can the technical team explain impurity limits and analytical instruments clearly? If answers change between sales and laboratory staff, pause. I would also inspect complaint handling and deviation reports, although suppliers may disclose only limited details. That weakness deserves reflection. A low quote can hide retesting costs, delayed delivery, or unstable specifications. Supplier evaluation should balance data, technical experience, documentation, and repeatable batch results.
Top Eight Chinese Suppliers and Their Market Profiles
China Top 8 Hydroxy 5 Nitroquinoline Supplier?
China’s hydroxy 5 nitroquinoline market includes eight notable supplier profiles, rather than one uniform supplier group. Some focus on research quantities, while others support repeat industrial orders. Several operate as custom synthesis partners with laboratory scale-up experience. Others mainly provide catalog chemicals through export channels. This difference matters when comparing price, lead time, and technical support.
A reliable supplier should provide a clear chemical name, CAS number, purity method, and batch-specific certificate of analysis. Buyers should also request water content, residual solvent data, impurity limits, and storage guidance. Experienced teams can explain packaging options, temperature control, and documentation for international transport. A practical sign is a responsive technical contact who answers specific questions, not only sales inquiries. Small sample availability helps verify appearance, solubility, and analytical consistency before larger purchasing decisions.
The strongest eight profiles may include manufacturers, custom producers, laboratory distributors, and export specialists. Their strengths are not identical. One may offer better analytical data, while another provides flexible batch sizes. Public information can also be incomplete or outdated. That is an uncomfortable limitation. Independent testing remains sensible, especially when specifications influence downstream research or manufacturing. Buyers should compare recent documents, production capability, communication quality, and delivery records before selecting a long-term Chinese supplier.
Quality Standards, Pricing Factors, and Procurement Considerations
China Top 8 Hydroxy 5 Nitroquinoline Supplier?
Selecting a reliable supplier requires more than comparing online rankings. A “top eight” list should reflect verified production records, not advertising claims. Request the compound’s exact chemical name, CAS number, molecular formula, and stated purity. Review the certificate of analysis carefully. It should include HPLC results, assay value, water content, residual solvents, and impurity limits. Independent testing is valuable when the material supports research or regulated manufacturing.
Pricing depends on purity, order volume, synthesis difficulty, packaging, and delivery terms. Small research quantities often cost more per gram. Ask whether the quotation includes testing, export documents, protective packaging, and shipping. Confirm the minimum order quantity and production lead time in writing. A low price may hide weaker testing or longer delivery. It is easy to overlook this detail.
Tips: Ask for a recent batch-specific COA, not a generic template. Compare analytical methods before comparing purity percentages. Check whether the supplier can provide samples and retain reference material. Clarify storage conditions, shelf life, and replacement terms. My checklist is not perfect, so I would record every response and revisit unclear points. Supplier communication can reveal practical reliability before payment.
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